Growing a baby is like running a marathon—your body is working extra hard for a long period of time, so it needs additional nutrition to make it through. That’s where prenatal vitamins come into play. They provide nutrients like folic acid, iron, calcium, and other vitamins to help support a healthy pregnancy, which is why both the American College of Obstetricians and Gynecologists (ACOG) and the Centers for Disease Control and Prevention (CDC) recommend taking them.
Here, we’ll review Perelel’s prenatal vitamins, including its first-, second-, and third-trimester supplements, which aim to offer targeted nutrients to support each stage of a person’s pregnancy. We tapped Karen Toubi, MD, a board-certified OB/GYN unaffiliated with Perelel, to take a look at the ingredients and help us determine whether the brand is a good choice.
Always talk to your OB/GYN first before starting a new supplement to determine if it’s right for you based on your individual health needs and any preexisting conditions.
The Perelel prenatal line
Perelel was co-founded by two moms who were frustrated by their experience with prenatal vitamins during pregnancy. Together, they partnered with a board-certified OB/GYN to create trimester-specific vitamin packs meant to disrupt the “one-size-fits-all” thinking around pregnancy supplements.
Quality-wise, Perelel checks all the boxes when it comes to a prenatal supplement: Its products are backed by clinical research, its facilities follow current Good Manufacturing Practices set by the FDA, and the products undergo third-party testing for purity and potency—in other words, they’re tested to confirm the vitamins actually have the ingredients on the label, in the amounts claimed, and that there are no additional, potentially harmful ingredients present, like heavy metals. This kind of testing is ideal in a prenatal supplement (or any supplement, for that matter) because, unlike medications, the FDA does not review or approve these products before they’re sold.
A monthly supply of Perelel prenatals costs around $60, but signing up for a monthly subscription knocks down the price to about $50 per month. Even with this discount, they’re on the pricier side compared to many other prenatals.
1st trimester pack
Perelel’s first trimester pack is formulated to support the early stages of a baby’s development and help reduce the nausea that can come with morning sickness. Dr. Toubi says the key ingredients include the following:
- Methylfolate: An active form of folate, important for the baby’s DNA synthesis and cell growth
- Iron: Supports increased blood volume and oxygen transport in the pregnant person’s body
- Vitamin B6: May help reduce nausea
- Ginger extract: Known for its anti-nausea properties
- DHA: Supports fetal brain development
The supplement’s anti-nausea component sets it apart from many other prenatals. “Vitamin B6 may help with nausea, while ginger has been traditionally used to alleviate digestive discomfort. This blend could be helpful for those dealing with mild to moderate morning sickness,” Dr. Toubi says.
Most notably, the supplement has methylfolate instead of folic acid. Both methylfolate and folic acid are supplemental forms of folate, which is crucial for healthy fetus development. Getting enough of this nutrient during pregnancy (especially early in pregnancy) helps prevent neural tube defects, or severe birth defects of the brain and spine.
But there’s some disagreement about whether methylfolate is as effective as folic acid at preventing these birth defects. In fact, the CDC says folic acid is the only form of folate proven to help prevent these defects, and ACOG recommends folic acid for this reason as well (at least 400 micrograms daily). At this time, although the studies on methylfolate are promising, there’s not enough research to say for certain that it’s as good of a choice as folic acid for preventing neural tube defects.
“If someone is taking methylfolate, they should ensure they are consuming adequate dietary folate and may consider a separate folic acid supplement if recommended by their healthcare provider, especially if they have a history of neural tube defects,” Dr. Toubi says.
1st Trimester Prenatal Pack
Pros
- Contains active forms of nutrients like methylfolate, which some folks may absorb better than synthetic forms
- The inclusion of ginger and B6 can be beneficial for managing morning sickness
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